
The blood is the part of milieu interior that circulates rapidly within a closed system of vessels.
The cerebrospinal fluid of central nervous system, the aqueous humor of eyes, and the fluid in the pleural and peritoneal cavities, joints, and the synovial sheaths are particular forms of interstitial fluid.
The blood plasma, which circulates rapidly through all organs of body.
The lymph contained in the lymphatic vessels, which circulates between tissues and blood. The interstitial or tissue fluids, which bathe the cells and circulate slowly. This milieu is formed by the extra cellular fluids, i.e. Muticellular organisms are surrounded by an external environment- air or water- but their cells live in a fluid environment which Claude Bernard in 1878 named the “milieu interior” (internal environment). When blood coagulates, it first becomes solid clot and then a fluid oozes out from clot, which is called the serum. Blood is made up of a liquid, the blood plasma, in which ells (erythrocytes, leukocytes, and platelets) and minute particles are suspended.
Between these last two compartments the exchange of diffusible substances is easy and continuous, so they have a similar content of water and salts. One is within the cells, the intracellular fluid and the other two, outside the cells and forming the extra cellularfluid and includes interstitial fluid and blood plasma. The body fluids are distributed in three compartments.